Cellular metabolism hijacked by viruses for immunoevasion: potential antiviral targets

Cellular metabolism plays a central role in the regulation of both innate and adaptive immunity. Immune cells utilize metabolic pathways to modulate cellular differentiation or death. The intricate interplay between immune response is critical for maintaining homeostasis effective antiviral activities. In recent years, immunometabolism induced by viral infections has been extensively investigated, accumulating evidence indicated that can be hijacked facilitate replication. Generally, virus-induced changes lead reprogramming metabolites enzymes different (glucose, lipid, amino acid metabolism). Metabolic affects function cells, regulates expression molecules determines cell fate. Therefore, it important explore effector with immunomodulatory properties, including metabolites, enzymes, other immunometabolism-related as antivirals. This review summarizes relevant advances field infections, providing novel insights development